The Biotransformation and Oxidative Stress Status (BOSS) research group is interested in research about the capabilities of the human liver to successfully detoxify all toxins the human body is exposed to. The main focus currently is on Chronic Fatigue Syndrome (a complex physical illness characterized by debilitating fatigue, post-exertional malaise, pain, cognitive problems, sleep dysfunction and an array of other immune, neurological and autonomic symptoms), and more recently also on biotransformation imbalances and the connection with certain cancer types.